Brain Circuit Analysis
Previously known as In vivo Brain Circuit Analysis
Brain Circuit Analysis will be a platform dedicated to studying neuronal circuits in health and disease using advanced methods for the perturbation and recording of cell activity. To that aim, a lab is being set up specifically for in vivo chronic recordings.
The new Brain Circuit Analysis platform will be located in A0956. A full description of the available equipment and services will be listed here soon.
As part of the previous In vivo Brain Circuit Analysis platform, the Inscopix nVue implantable miniature microscope system (https://inscopix.com/nvue-system/) is available for interested researchers. Description from the former platform:
The Inscopix Miniature microscope system allows to image large-scale brain circuit dynamics via in vivo calcium imaging in freely behaving animals to correlate neural activity with behaviour. nVue enables imaging of two distinct brain signals to gain deeper insight into how an ensemble of brain signals interacts during free behaviour in a single imaging session.
- Image two distinct cellular populations from shallow or deep brain regions simultaneously with single-cell resolution
- Explore the relationship of up to two brain signals during naturalistic behaviour
- Record multi-channel data using nVue’s expanded data storage, facilitating longitudinal data acquisition over months
The Inscopix nVue system is basically a miniature microscope that can be attached to implanted GRIN lenses. Light, emitted by e.g. Calcium indicators, can be recorded at a single cell resolution in freely behaving animals.
Included in the platform:
Inscopix Miniscope system
- nVUE System for Dual Colour in vivo Imaging
- Application module (Baseplate covers, Dummy scope)
- Data acquisition box (DAQ)
- Data acquisition software
- Software licence
- ProView Implant Kit (Lens holding device, stereotax rod, screw adjustment tool)
- Inscopix care (free repairs, overnight shipping on ALL components)