Experimental Dementia Research

Dementia is a growing health concern worldwide as populations age. In Alzheimer’s disease and Parkinson’s disease, dementia is a major symptom that requires better therapies. These common diseases show overlapping/mixed dementia pathologies. 

Our group focus on the earliest subcellular pathological changes in synapses and is increasingly turning to therapeutic research, in particular immunotherapy, to reverse these early alterations. We use various approaches in which the scientific question drives the methods that are chosen to provide new and impactful insights.

Our research is primarily focused on mechanistic understanding to support the development of improved therapy. In addition, we collaborate locally with clinical researchers on related preclinical projects to potentially help improve clinical diagnosis. Taken together, our projects contribute to MultiPark’s strategic goals to improve diagnosis, understanding, and treatment of neurodegenerative disorders.