Our research

My team focuses on developing accurate methods for early diagnosis of Alzheimer's and Parkinson's disease related disorders. We also aim to unravel the interplay between different pathologic events in humans with pre-symptomatic or prodromal disease, as well as to investigate different subtypes of the diseases.  Finally, we are focusing on improving clinical trials evaluating new disease-modifying therapies for Alzheimer's and Parkinson's disease related disorders.

An overview of our research cohorts can be found at BioFINDER. 

Aims

• Revolutionize the diagnostic and prognostic methods for timely diagnosis of Alzheimer's and Parkinson's disease related disorders.

• Substantially improve the design of clinical trials evaluating novel disease-modifying therapies in individuals with pre-symptomatic or prodromal disease.

• Study the order of molecular events occurring in the diseases, and identify and study different relevant subtypes of the diseases.

• Take part in the development and validation of effective therapies for early disease.

Impact

Our time- and cost-effective diagnostic and prognostic models will likely democratize the diagnostics of Alzheimer's disease globally. Hopefully, we will also be able to improve the early diagnostics of other related disorders, like Parkinson's disease. 

Effective disease-modifying therapies that can be initiated during the earliest disease stages of these disorders would have a substantial impact on not only the affected individuals but also on the health-care economics and society as a whole.

How our research contributes to the goals of MultiPark

 Our research addresses the aims of MultiPark's working groups 5 and 6. 

Research Team & Publications

Read about publications and research team members of the Clinical Memory Research Unit in the LU Research Portal.

For an overview of the research focus, read the invited review about biomarkers in Nature Medicine.